| Date | Heure | Terrain | Receveur | Résultat | Visiteur |
| 2022-05-07 | 14:00 | Cégep Montmorency | FC Laval | 2-1 | Pierrefonds FC |
| 2022-05-07 | 16:00 | Stade Beauport | Royal Sélect Beauport | 1-2 | AS Blainville |
| 2022-05-07 | 17:00 | Quinn’s Pointe Field | Ottawa South United | 2-1 | CS St-Hubert |
| 2022-05-07 | 18:00 | Parc Renaud-Maillette | Rapides Chaudière-Ouest | 1-0 | CS Longueuil |
| 2022-05-07 | 18:30 | TMR REC 3 | CS Mont-Royal Outremont | 1-2 | Celtix du Haut-Richelieu |
| 2022-05-07 | 19:00 | Lausanne 1 | AS Laval | 2-3 | PEF Soccer Québec |
| 2022-05-14 | 17:00 | Quinn’s Pointe Field | Ottawa South United | 0-1 | CS Mont-Royal Outremont |
| 2022-05-14 | 18:00 | Stade Desjardins | PEF Soccer Québec | 1-2 | FC Laval |
| 2022-05-14 | 18:00 | PCHS 1 | Pierrefonds FC | 4-0 | Royal Sélect Beauport |
| 2022-05-14 | 19:00 | Parc Blainville 1 | AS Blainville | 3-3 | Rapides Chaudière-Ouest |
| 2022-05-14 | 19:15 | Laurier 1 | CS Longueuil | 0-0 | Celtix du Haut-Richelieu |
| 2022-05-15 | 14:00 | Rosanne Laflamme | CS St-Hubert | 0-2 | AS Laval |
| 2022-05-21 | 15:00 | Lausanne 1 | AS Laval | 3-1 | Ottawa South United |
| 2022-05-21 | 18:00 | Alphonse-Desjardins | Celtix du Haut-Richelieu | 0-4 | AS Blainville |
| 2022-05-21 | 18:00 | Parc Renaud-Maillette | Rapides Chaudière-Ouest | 3-0 | Pierrefonds FC |
| 2022-05-21 | 18:30 | TMR REC 3 | CS Mont-Royal Outremont | 0-1 | CS Longueuil |
| 2022-05-22 | 16:00 | Stade Beauport | Royal Sélect Beauport | 1-2 | PEF Soccer Québec |
| 2022-05-22 | 20:00 | Cégep Montmorency | FC Laval | 3-1 | CS St-Hubert |
| 2022-05-28 | 13:00 | Quinn’s Pointe | Ottawa South United | 1-3 | FC Laval |
| 2022-05-28 | 18:00 | Stade Desjardins | PEF Soccer Québec | 0-0 | Rapides Chaudière-Ouest |
| 2022-05-28 | 18:00 | PCHS 1 | Pierrefonds FC | 2-1 | Celtix du Haut-Richelieu |
| 2022-05-28 | 19:00 | Parc Blainville 1 | AS Blainville | 1-0 | CS Longueuil |
| 2022-05-28 | 19:00 | Lausanne 1 | AS Laval | 3-0 | CS Mont-Royal Outremont |
| 2022-05-29 | 14:00 | Rosanne Laflamme | CS St-Hubert | 1-0 | Royal Sélect Beauport |
| 2022-06-04 | 16:00 | Stade Beauport | Royal Sélect Beauport | 8-0 | Ottawa South United |
| 2022-06-04 | 17:00 | Pierre-Benoît | Celtix du Haut-Richelieu | 0-4 | PEF Soccer Québec |
| 2022-06-04 | 18:00 | Cégep Montmorency | FC Laval | 0-1 | AS Laval |
| 2022-06-04 | 18:00 | Complexe Honco | Rapides Chaudière-Ouest | 4-1 | CS St-Hubert |
| 2022-06-04 | 18:30 | TMR REC 3 | CS Mont-Royal Outremont | 0-1 | AS Blainville |
| 2022-06-05 | 19:15 | Laurier 1 | CS Longueuil | 1-1 | Pierrefonds FC |
| 2022-06-11 | 18:00 | Cégep Montmorency | FC Laval | 0-3 | CS Mont-Royal Outremont |
| 2022-06-11 | 18:00 | Stade Desjardins | PEF Soccer Québec | 1-2 | CS Longueuil |
| 2022-06-11 | 18:00 | PCHS 1 | Pierrefonds FC | 0-0 | AS Blainville |
| 2022-06-11 | 18:30 | Quinn’s Pointe Field | Ottawa South United | 2-3 | Rapides Chaudière-Ouest |
| 2022-06-11 | 19:00 | Lausanne 1 | AS Laval | 2-0 | Royal Sélect Beauport |
| 2022-06-12 | 14:00 | Rosanne Laflamme | CS St-Hubert | 1-4 | Celtix du Haut-Richelieu |
| 2022-06-18 | 13:00 | Alphonse-Desjardins | Celtix du Haut-Richelieu | 3-4 | Ottawa South United |
| 2022-06-18 | 16:00 | Stade Beauport | Royal Sélect Beauport | 2-3 | FC Laval |
| 2022-06-18 | 17:00 | Parc Blainville 1 | AS Blainville | 3-0 | PEF Soccer Québec |
| 2022-06-18 | 18:00 | PCHS 1 | Pierrefonds FC | 0-1 | CS Mont-Royal Outremont |
| 2022-06-18 | 18:00 | ESLE | Rapides Chaudière-Ouest | 0-1 | AS Laval |
| 2022-06-18 | 19:15 | Laurier 1 | CS Longueuil | 1-1 | CS St-Hubert |
| 2022-06-25 | 13:00 | Richcraft | Ottawa South United | 1-0 | CS Longueuil |
| 2022-06-25 | 18:00 | Cégep Montmorency | FC Laval | 0-0 | Rapides Chaudière-Ouest |
| 2022-06-25 | 18:00 | Stade Desjardins | PEF Soccer Québec | 1-2 | Pierrefonds FC |
| 2022-06-25 | 18:30 | TMR REC 3 | CS Mont-Royal Outremont | 0-2 | Royal Sélect Beauport |
| 2022-06-25 | 19:00 | Lausanne 1 | AS Laval | 6-0 | Celtix du Haut-Richelieu |
| 2022-06-26 | 14:00 | Rosanne Laflamme | CS St-Hubert | 0-5 | AS Blainville |
| 2022-07-02 | 13:00 | Alphonse-Desjardins | Celtix du Haut-Richelieu | 0-2 | FC Laval |
| 2022-07-02 | 19:00 | PCHS 1 | Pierrefonds FC | 3-0 | CS St-Hubert |
| 2022-07-02 | 18:00 | ESLE | Rapides Chaudière-Ouest | 3-1 | Royal Sélect Beauport |
| 2022-07-02 | 18:30 | TMR REC 3 | CS Mont-Royal Outremont | 1-0 | PEF Soccer Québec |
| 2022-07-02 | 19:15 | Laurier 1 | CS Longueuil | 0-0 | AS Laval |
| 2022-07-03 | 18:00 | Parc Blainville 1 | AS Blainville | 3-1 | Ottawa South United |
| 2022-07-09 | 14:00 | Cégep Montmorency | FC Laval | 1-0 | CS Longueuil |
| 2022-07-09 | 16:00 | Quinn’s Pointe Field | Ottawa South United | 3-2 | Pierrefonds FC |
| 2022-07-09 | 16:00 | Stade Beauport | Royal Sélect Beauport | 2-2 | Celtix du Haut-Richelieu |
| 2022-07-09 | 18:00 | ESLE | Rapides Chaudière-Ouest | 4-2 | CS Mont-Royal Outremont |
| 2022-07-09 | 19:00 | Lausanne 1 | AS Laval | 1-1 | AS Blainville |
| 2022-07-10 | 14:00 | Rosanne Laflamme | CS St-Hubert | 1-5 | PEF Soccer Québec |
| 2022-07-16 | 13:00 | Alphonse-Desjardins | Celtix du Haut-Richelieu | 0-4 | Rapides Chaudière-Ouest |
| 2022-07-16 | 17:00 | Parc Blainville 1 | AS Blainville | 3-2 | FC Laval |
| 2022-07-23 | 18:00 | Stade Desjardins | PEF Soccer Québec | 2-2 | Ottawa South United |
| 2022-07-16 | 19:00 | PCHS 1 | Pierrefonds FC | 0-1 | AS Laval |
| 2022-07-16 | 18:30 | TMR REC 3 | CS Mont-Royal Outremont | 4-0 | CS St-Hubert |
| 2022-07-16 | 19:15 | Laurier 1 | CS Longueuil | 4-1 | Royal Sélect Beauport |